abstract：BACKGROUND AND OBJECTIVE:Our objective was to assess the frequency of fungal colonization and/or infection in critically ill patients admitted to intensive care units (ICUs) and to describe the characteristics and risk factors of those patients in whom fungi had been isolated. PATIENTS AND METHOD:Observational, multic...

journal_title：Medicina clinica

authors： Alvarez-Lerma F,Palomar M,León C,Olaechea P,Cerdá E,Bermejo B,Grupo de Estudio de Infeción Fúngica.

更新日期：2003-07-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The suitable antibiotic(s) and duration of treatment for hip prosthesis acute infections (HPAIs) has not been clearly defined. PATIENTS AND METHOD:We studied 32 patients whose HPAI was diagnosed within 2 months after surgery. All patients underwent debridement and samples were taken for cultur...

journal_title：Medicina clinica

authors： Soriano A,García S,Ortega M,Almela M,Gallart X,Vila J,Sierra J,Tomas X,Martínez JA,Mensa J

更新日期：2003-06-21 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The epidemiology of hepatitis A, E, B and C was analyzed in 1,393 children living in Santa Cruz de la Sierra, Bolivia. They were distributed in two groups according to the social condition. MATERIALS AND METHOD:1,393 children were selected from two different schools: one attended by children ...

journal_title：Medicina clinica

authors： Gandolfo GM,Ferri GM,Conti L,Antenucci A,Marrone R,Frasca AM,Vitelli G

更新日期：2003-05-24 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The correct management of patients with chronic renal disease depends on an early diagnosis. The aim of this study was to evaluate the usefulness, in the daily clinical practice, of the weight/creatinine formula as an indirect measurement of glomerular filtration. PATIENTS AND METHOD:1,025 amb...

journal_title：Medicina clinica

authors： Fernández-Fresnedo G,Martín de Francisco AL,Rodrigo Calabia E,Ruiz San Millán JC,Sanz de Castro S,Arias Rodríguez M

更新日期：2003-04-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:A good metabolic control of patients with type 2 diabetes mellitus (DM2) will likely contribute to a decrease of their cardiovascular (CV) risk. Our aim was (1) to evaluate the degree of metabolic control with regard to glycemia, lipidemia and blood pressure (BP) and (2) to describe the prevale...

journal_title：Medicina clinica

authors： de la Calle H,Costa A,Díez-Espino J,Franch J,Goday A

更新日期：2003-04-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the ability of long-term highly active antiretroviral therapy (HAART) to fully reconstitute the immune system in children with severe AIDS. PATIENT AND METHOD:Lymphoproliferative responses (LPR) were evaluated by incorporation of [3H]-thymidine. Cytokine p...

journal_title：Medicina clinica

authors： Resino S,Sánchez-Ramón S,Correa R,Navarro ML,Bellón JM,Muñoz-Fernández MA

更新日期：2003-03-29 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Anxiety and depression are common among medical inpatients. While their relation to the severity of illness is often discussed, the feeling of such severity by the patient and his/her prospects of improvement can be influenced by anxiety and depression. PATIENTS AND METHOD:Patients admitted in...

journal_title：Medicina clinica

authors： Grau Martín A,Suñer Soler R,Abulí Picart P,Comas Casanovas P

更新日期：2003-03-22 00:00:00

abstract：BACKGROUND AND OBJECTIVE:A common Leu7Pro polymorphism in the signal peptide of neuropeptide Y has been associated with increased plasma cholesterol and accelerated atherosclerosis in the Finnish population. SUBJECTS AND METHOD:A cross-sectional design was carried out in 1,000 individuals from the Mediterranean Spanis...

journal_title：Medicina clinica

authors： Portolés O,Sorlí JV,González JI,Ruiz de la Fuente S,Ramírez JB,Corella D

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Our goal was to determine the incidence of infection due to Mycobacterium kansasii in Elche, Spain over the last 10 years and to study the activity of new antibiotics against the strains isolated. MATERIAL AND METHODS:A retrospective study of patients and study of antibiotic susceptibility in ...

journal_title：Medicina clinica

authors： Rodríguez JC,Ayelo A,Ruiz M,López M,Royo G

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We pursued here to determine the incidence of blood-stream infections. PATIENTS AND METHOD:Longitudinal descriptive study. All patients admitted to hospital from January 1999 to December 2000 were included. Blood-stream infection episodes were defined according to CDC criteria. Blood-stream in...

journal_title：Medicina clinica

authors： Bou R,Perpiñán J,Ramos P,Peris M,Aguilar A,Garcés R

更新日期：2003-02-22 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this paper was determine the prevalence of antibodies against Francisella tularensis in the representative sample of people from Castilla-León (Spain) before epidemic outbreak of end 1997. SUBJECTS AND METHOD:We obtain 4,825 sera (between april-1996 and april-1997) of people from C...

journal_title：Medicina clinica

authors： Gutiérrez MP,Orduña A,Dueñas A,Bratos MA,Almaraz A,Alamo R,Rodríguez Recio MJ,Rodríguez Marcos H,Rodríguez Torres A

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Fetal microchimerism (FM) has been implicated in the pathogenesis of primary biliary cirrhosis (PBC). The aim of the study was to investigate the presence of FM in PBC patients. PATIENTS AND METHOD:FM was studied in 28 women, 14 with PBC and 14 healthy controls.DNA was extracted from peripheral blood cells,...

journal_title：Medicina clinica

authors： Selva O'Callaghan A,Balada Prades E,Castells Fusté L,Vargas Blasco V,Solans Laque R,Vilardell Tarrés M

更新日期：2002-12-07 00:00:00

abstract：BACKGROUND:The purpose of this study was to know the concordance of diagnosis between emergency rooms amd hospitalization wards and to analyze the mistake index, the epidemiological characteristics and the main reasons for the mistakes. PATIENTS AND METHOD:We analyzed hospitalized patients and used a three-level conco...

journal_title：Medicina clinica

authors： Tudela P,Mòdol JM,Veny A,Tor J,Bonet M,Rego MJ

更新日期：2002-10-26 00:00:00

abstract：BACKGROUND:It is estimated that 5-10% of breast cancers have an hereditary origin, germline mutations of BRCA1 and BRCA2 genes causing a predisposition. In the present study we analyzed BRCA1 and BRCA2 mutations in moderate to high risk breast cancer patients in order to find out the types and frequency of these mutati...

journal_title：Medicina clinica

authors： Velasco Sampedro E,Esteban Cardeñosa E,Infante Sanz M,Durán Domínguez M,Lastra Aras E,García Girón C,Miner Pino C

更新日期：2002-10-12 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) is one of the most frequent infectious disease conditions. With the aim of knowing the diagnostic and therapeutic strategies of CAP in Spanish hospitals we performed a prospective, observational and multicenter study. PATIENTS AND METHOD:Observational study of 468 patients...

journal_title：Medicina clinica

authors： Celis MR,Torres A,Zalacaín R,Aspa J,Blanquer J,Blanquer R,Gallardo J,España PP,Grupo de trabajo del Area TIR para el estudio del diagnóstico y tratamiento de la NAC en España (NACE).

更新日期：2002-09-21 00:00:00

abstract：BACKGROUND:Group therapy is a widely used technique for the treatment of tobacco, alcohol and other toxic addictions. Nevertheless, its effectiveness for smoking cessation remains to be established. Our objective was to evaluate the relative effectiveness of a group intervention versus an individual intervention for sm...

journal_title：Medicina clinica

authors： Camarelles F,Asensio A,Jiménez-Ruiz C,Becerril B,Rodero D,Vidaller O

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:Our goal was to investigate the epidemiological characteristics and etiology of an outbreak of food-borne disease caused by Norwalk-like viruses, genogroup II. PATIENTS AND METHOD:We performed a historical cohort study on the consumption of 21 food items and clinical symptoms. We assessed RNA Norwalk-like v...

journal_title：Medicina clinica

authors： Godoy P,Prat A,Alsedà M,Torres J,Domínguez A,Salleras L

更新日期：2002-06-08 00:00:00

abstract：BACKGROUND:Primary pulmonary hypertension is a poorly understood disease with a difficult treatment. PATIENTS AND METHOD:Retrospective study of a series of 44 patients suffering from pulmonary hypertension who were studied in our center between 1992 and 2000. RESULTS:At diagnosis, 6 (13%) patients were classified as ...

journal_title：Medicina clinica

authors： Roman A,Rodés-Cabau J,Lara B,Bravo C,Monforte V,Pallissa E,Domingo E,Morell F

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Our goal was to analyze the relationship of lipids and lipoproteins, APOE genotype and mutations of the LDL receptor gene with the prevalence of myocardial infarction (MI) in patients with familial hypercholesterolemia (FH) from a Southern European FH population. PATIENTS AND METHOD:We studied 108 heterozyg...

journal_title：Medicina clinica

authors： Real JT,Ascaso JF,Chaves FJ,González C,Puig O,Armengod ME,Carmena R

更新日期：2002-05-18 00:00:00

abstract：BACKGROUND:Few reports have analysed the transmission of tuberculosis in rural areas with a low incidence of disease. PATIENTS AND METHOD:A population-based molecular epidemiological study of patients with tuberculosis, diagnosed by culture, was conducted in Segovia (Spain) between 1995 and 1999. Clinical, demographic...

journal_title：Medicina clinica

authors： Elizaga J,Carrero P,Iñigo J,Chaves F

更新日期：2002-05-11 00:00:00

abstract：BACKGROUND:Deep vein thrombosis (DVT) is a difficult to diagnostic disease. The aim of this study was to determine the utility and accuracy of a risk stratification questionnaire and a diagnostic strategy, which were applied to patients with suspected DVT on lower extremities in an emergency department. PATIENTS AND M...

journal_title：Medicina clinica

authors： Ruiz-Giménez N,Friera A,Sánchez Moliní P,Caballero P,Rodríguez-Salvanés F,Suárez C,Representacion del grupo de estudio de Enfermedad Tromboembolica (ETEV) del Hospital Universitario La Princesa.

更新日期：2002-04-20 00:00:00

abstract：BACKGROUND:Recent advances in sensitivity and specificity of hormone immunoanalysis and their automatization have brought about changes in clinical laboratories that led us to review the need for some endocrine dynamic tests. The specific aim of this study was to determine the basal cortisol values predicting a normal ...

journal_title：Medicina clinica

authors： Alfayate R,Mauri M,de Torre M,Pardo C,Picó A

更新日期：2002-04-06 00:00:00

abstract：BACKGROUND:Our main goals were to know the actual degree of oral anticoagulation and antiaggregation in hypertensive patients with atrial fibrillation in the daily clinical practice in Spain and to analyze any differences between primary care physicians and cardiologists. PATIENTS AND METHOD:32,051 outpatients attende...

journal_title：Medicina clinica

authors： Bertomeu Martínez V,Morillas Blasco PJ,González Juanatey JR,Alegría Ezquerra E,García Acuña JM,González Maqueda I,Frutos García A,Valero Parra R,Rodríguez Ortega JA

更新日期：2002-03-16 00:00:00

abstract：BACKGROUND:Since 1992 conservative treatment of breast cancer (stage I and II: clinical TNM) has been established as an alternative to mastectomy in our hospital. The aim of this retrospective study was to analyse locoregional recurrence features and to compare prognosis with regard to to site of recurrence. METHOD:Be...

journal_title：Medicina clinica

authors： Fuentes Raspall MJ,Piedrafita Serra E,Isern Verdum J,Alonso Muñoz C,Ojeda González B,Gómez Gómez A,Llauradó Ollé A,Duarte Pires D,Lerma Puertas E,Craven-Bartle Lamote De Grignon J,López López A,Trias Folch M

更新日期：2002-02-16 00:00:00

abstract：BACKGROUND:We aimed at assessing the pulmonary function and life quality of patients with bronchiectasis not caused by cystic fibrosis (CF) on the basis of the presence or absence of colonization (with Pseudomonas or other microorganisms). PATIENTS AND METHOD:Prospective, randomised control-case study of patients with...

journal_title：Medicina clinica

authors： Hernández C,Abreu J,Jiménez A,Fernández R,Martín C

更新日期：2002-02-09 00:00:00

abstract：BACKGROUND:Whether or not performing cardiopulmonary resuscitation (CPR) is a complex decision that requires taking account of several factors. The aim of this study was to analyse the preferences of elderly people with regard to CPR. SUBJECTS AND METHOD:Survey administered to 181 elderly subjects from nursing homes a...

journal_title：Medicina clinica

authors： Reig L,Fernández M,García M,Martín-Baranera M

更新日期：2002-02-02 00:00:00

abstract：BACKGROUND:Lateral chest X-rays may be helpful in the early detection of osteoporotic patients. We studied the proportion of chest X-ray reports in which the radiologist highlighted the presence of vertebral osteoporotic signs, as well as the proportion of patients with such records who were further studied by their ph...

journal_title：Medicina clinica

authors： Hernández Hernández JL,Fidalgo González I,López-Calderón M,Olmos Martínez JM,González Macías J

更新日期：2001-12-08 00:00:00

abstract：BACKGROUND:The presence of the 5569A polymorphism may lead to misdiagnosis of patients susceptible of hereditary hemochromatosis (HH). For that reason, samples containing the Cys282Tyr mutation were revised and the frequency of this polymorphism in our environment was assessed. PATIENTS AND METHOD:Twenty samples were ...

journal_title：Medicina clinica

authors： Román R,Colomer A,Erill N,Puig X,Guix M

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:We describe the characteristics of people with a recent diagnosis of HIV infection. PATIENTS AND METHOD:Series of 126 new cases of HIV infection diagnosed in an infectious diseases Service. RESULTS:Sexual transmission was the commonest form of infection (74%). Fifteen percent of individuals were aged over ...

journal_title：Medicina clinica

authors： López De Munain J,Cámara MM,Santamaría JM,Zubero Z,Baraia-Etxaburu J,Muñoz J

更新日期：2001-11-24 00:00:00

abstract：UNLABELLED:This was a study aimed to know the knowledge about asthma. SUBJECTS AND METHOD:933 teachers of 27 schools from 7 cities (children aged between 4 and 15 years) using a self-administered questionnaire Half of them knew asthma prevalence and its hereditary nature. Nearly all related asthma with allergy, 38% wi...

journal_title：Medicina clinica

authors： Cobos N,Picado C,Grupo CESEA.

更新日期：2001-10-20 00:00:00

abstract：BACKGROUND:To evaluate the possible protector role of Lactobacillus against vaginal candidiasis. PATIENTS AND METHOD:In vitro studies performed to assess the capacity of 15 Lactobacillus strains to block the adhesion of two Candida albicans and one C. glabrata strain to vaginal epithelial cells and to inhibit the grow...

journal_title：Medicina clinica

authors： Osset J,García E,Bartolomé RM,Andreu A

更新日期：2001-09-22 00:00:00

abstract：BACKGROUND:The objective of this study was to identify the risk factors associated with the nosocomial sepsis syndrome according to the criteria of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. PATIENTS AND METHOD:A 1-year prospective case-control study matched for se...

journal_title：Medicina clinica

authors： Fariñas Alvarez C,Carmen Fariñas M,Llorca J,Delgado Rodríguez M

更新日期：2001-06-02 00:00:00

abstract：BACKGROUND:To know the clinical and epidemiologic characteristics, the evolution and the rate of adequate empiric antibiotic treatment in adult patients with a bacteremia discovered after discharge from an emergency unit. PATIENTS AND METHOD:During 10 years (1989-1998), we registered the clinical and epidemiological d...

journal_title：Medicina clinica

authors： Javaloyas M,Jarné J,García D,Gudiol F

更新日期：2001-05-19 00:00:00

abstract：BACKGROUND:The presence of cagA antibodies constitutes a serum marker of infection caused by virulent strains of Helicobacter pylori. The objective of this study was to determine the risk of peptic ulcer in patients with H. pylori infection, in relation to the detection of CagA and VacA antibodies. PATIENTS AND METHOD...

journal_title：Medicina clinica

authors： Santolaria S,Lanas A,Benito R,Piazuelo E,Sáinz R

更新日期：2001-05-12 00:00:00

abstract：BACKGROUND:To relate the renal hemodynamic changes, as assessed by Doppler ultrasonography,with the development of ascites, renal function, and endogenous vasoactive systems in patients with liver cirrhosis. PATIENTS AND METHODS:60 cirrhotic patients were studied prospectively, 31 of these compensated and 29 with asci...

journal_title：Medicina clinica

authors： Rendón Unceta P,Macías Rodríguez MA,Guillén Mariscal P,Tejada Cabrera M,Martínez Sierra MC,Martín Herrera L

更新日期：2001-04-28 00:00:00

abstract：BACKGROUND:A right information about illness is essential if a patient has to take ethically autonomous medical decisions. We assessed whether a group o patients with chronic obstructive pulmonary disease (COPD) had enough information about their illness to take medical decisions. PATIENTS AND METHOD:Structured interv...

journal_title：Medicina clinica

authors： Miró Andreu G,Félez Flor M,Solsona Durán JF

更新日期：2001-04-21 00:00:00

abstract：BACKGROUND:B-mode ultrasonography is a simple and valid method to evaluate subclinical atherosclerosis of the major superficial arteries. The aim of this study was toknow by this technique the prevalence of carotid atherosclerosisin patients with coronary disease and related factors. PATIENTS AND METHOD:In 232patients...

journal_title：Medicina clinica

authors： Fernández-Miranda C,Luis Aranda J,Paz M,Núñez V,Gómez González P,Díaz-Rubio P,Larumbe S,Teresa Gómez Izquierdo M

更新日期：2001-03-31 00:00:00

abstract：BACKGROUND:Human obesity is a widespread disease with considerable variability as to its severity, metabolic and endocrine manifestations and etiology. In the present study we have determined whether the alterations of uncomplicated severe obesity in adult young women affect with different intensity the circulating lev...

journal_title：Medicina clinica

authors： Vilà R,Gutiérrez R,Luisa Granada M,María Masanés R,del Mar Grasa M,Antonio Fernández López J,Remesar X,Formiguera X,Foz M,Alemany M

更新日期：2001-03-10 00:00:00

abstract：BACKGROUND:Description of measures of secondary prevention and of health related quality of life one year after the intervention in patients undergoing coronary artery bypass surgery. PATIENTS AND METHOD:One year follow up prospective study in patients undergoing first coronary bypass surgery without associated proced...

journal_title：Medicina clinica

authors： Brotons Cuixart C,Moral Peláez I,Permanyer Miralda G,Ribera Solé A,Cascant Castelló P,Estudio CIRCORCA.

更新日期：2001-02-24 00:00:00

abstract：BACKGROUND:To evaluate differences in the temporal profile of acute phase response (APR) between ischemic stroke (IS) and intracerebral hemorrhage (ICH). PATIENTS AND METHOD:We studied APR parameters (< 24 h and 3-5 day) in 88 consecutive patients (43 ICH and 45 IS). The increase/decrease of the parameters between bot...

journal_title：Medicina clinica

authors： Montaner,Alvarez-Sabín J,Abilleira S,Molina C,Arenillas J,Codina A

更新日期：2001-01-20 00:00:00